The Science of Thermic Effect of Food and Macros

2 weeks, 3 days ago Calculating Macros & Calories
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ScienceSam Guest
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Mar 29, 2026 20:12

I have been reading about the thermic effect of food (TEF) and how protein takes more energy to digest than fats or carbs. Does this mean that 2000 calories of protein is actually less net calories than 2000 calories of fat?

It seems like a small detail but over the course of a day it could add up to 100 or 200 calories. I am wondering if this is why high protein diets are so effective for fat loss. It is not just about the satiety but also the energy cost of digestion.

Do any of you take TEF into account when calculating your TDEE or do you just consider it a bonus? I find the metabolic side of nutrition so fascinating and I would love to hear your thoughts on how much this actually matters for the average lifter.

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